Quick answer

You can't get Spravato (esketamine) nasal spray online or use it at home. Under the FDA's REMS safety program it's only given at certified treatment centers: you use the spray in person while a healthcare provider watches, then stay for at least 2 hours of monitoring. Our in-person Spravato is at Calm Clinic in Las Vegas.

Spravato (Esketamine) Online? Why It's Only Given In Person

Spravato (Esketamine) Online? Why It's Only Given In Person

In person only · Calm Clinic, Las Vegas

Quick answer

You can't get Spravato (esketamine) nasal spray online or use it at home. Under the FDA's REMS safety program it's only given at certified treatment centers: you use the spray in person while a healthcare provider watches, then stay for at least 2 hours of monitoring. Our in-person Spravato is at Calm Clinic in Las Vegas.

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Spravato (esketamine) nasal spray is FDA-approved for treatment-resistant depression in adults and for depressive symptoms in adults with major depressive disorder who have acute suicidal thoughts or actions. Because it can cause sedation, dissociation and slowed breathing, the FDA's REMS program allows it only at certified treatment centers: you use the spray in person while a healthcare provider watches, then stay for at least 2 hours of monitoring. It can't be ordered online or taken at home.

Near Las Vegas

Get Spravato in person at Calm Clinic in Las Vegas, 4029 Dean Martin Dr, Las Vegas, NV 89103. Consults are with Dr. Grant Bullock, DO.

Not near Las Vegas

Ask your own clinician about a certified Spravato center near you, or see whether an at-home ketamine evaluation by video fits. Ketamine is a different medication, and it isn't right for everyone.

About at-home ketamine

Getting care is simple

1

Book a consult

Book a Spravato consult online or call (702) 848-2256. Consults are at our Las Vegas office. Use your Nevada plan or pay $150 for the visit.

2

Consult and benefits check

Your clinician reviews your diagnosis, the antidepressants you've tried and your blood pressure. If Spravato fits, you're enrolled in the REMS program and we check what your plan covers.

3

Supervised treatment sessions

You use the nasal spray at the clinic and stay for at least 2 hours of monitoring. Plan a ride home.

What to expect from your care

Spravato is a prescription nasal spray you use yourself at a certified treatment center, while a healthcare provider watches. It's never sent home with you.

  • FDA-approved for treatment-resistant depression in adults
  • Given only at REMS-certified treatment centers
  • At least 2 hours of monitoring after every dose
  • In person at Calm Clinic in Las Vegas

Searching for Spravato online?

People often search for "Spravato online," an online Spravato prescription, or esketamine nasal spray to use at home. You can't get Spravato any of those ways. Under the Spravato REMS, certified pharmacies send Spravato only to certified healthcare settings, never to patients. Every dose is taken there under a healthcare provider's direct observation, followed by at least 2 hours of monitoring, and a telehealth visit can't replace that session. If a website offers to sell or ship esketamine to you, it isn't following these rules.

What you can do instead:

  • If you live in or near Las Vegas, come to Calm Clinic in Las Vegas for in-person Spravato. Book a Spravato consult online or call (702) 848-2256.
  • If you live somewhere else, ask your psychiatric clinician about a certified Spravato treatment center near you.
  • If you want care by video, ask about our at-home ketamine evaluation. Ketamine is a different medication from Spravato. It's prescribed off-label, it isn't FDA-approved for any psychiatric condition, and it isn't right for everyone. A licensed clinician decides whether it fits you after an evaluation.

We can't prescribe controlled substances, including ketamine, in Alabama, Arkansas, Hawaii, Louisiana, Maine, Massachusetts, Minnesota, Missouri, Oklahoma, Pennsylvania and West Virginia, and we don't offer ketamine in Texas. Federal telehealth rules for controlled substances are temporary through Dec 31, 2026 and may change.

Where we give Spravato

We give Spravato only in person, at Anywhere Clinic's Las Vegas office, 4029 Dean Martin Dr, Las Vegas, NV 89103. See Spravato in Las Vegas at Calm Clinic for the office and its other services. Spravato consults there are with Dr. Grant Bullock, DO. Book a Spravato consult online or call (702) 848-2256.

Spravato is for adults; it isn't approved for children or teens. If you'd rather not add a medication, TMS therapy in Las Vegas is a non-drug treatment for depression given at the same office.

Who Spravato is approved for

  • Treatment-resistant depression in adults, used on its own or with an oral antidepressant. In the clinical trials, this meant major depression that hadn't improved enough after at least two different antidepressants, each taken at an adequate dose for an adequate time.
  • Depressive symptoms in adults with major depressive disorder who have acute suicidal thoughts or actions, used with an oral antidepressant.

Spravato isn't recommended during pregnancy because it may harm an unborn baby, and breastfeeding isn't recommended during treatment. Tell your clinician if you're pregnant or planning a pregnancy.

Spravato hasn't been shown to prevent suicide or reduce suicidal thoughts, and it doesn't replace a hospital stay when one is needed. If you're in crisis now, call or text 988 or go to the nearest emergency room. Whether Spravato is right for you is your clinician's decision after an evaluation.

What a Spravato treatment course looks like

For treatment-resistant depression, the label's schedule is:

  • Weeks 1 to 4: two sessions a week.
  • Weeks 5 to 8: one session a week.
  • Week 9 on: one session every week or every 2 weeks, at the least frequent schedule that keeps you well.

Your clinician checks whether it's helping at the end of the first 4 weeks. For depressive symptoms with acute suicidal thoughts or actions, the course is two sessions a week for 4 weeks.

At each session your blood pressure is checked before and after the dose and your breathing is monitored. Don't eat for 2 hours or drink for 30 minutes beforehand, since nausea and vomiting can happen. You can't drive or operate machinery until the next day after a restful sleep, so plan a ride home.

Insurance for Spravato in Nevada

Spravato consults at Calm Clinic are in network with these Nevada plans:

  • Aetna
  • Anthem / Carelon
  • Cigna / Evernorth
  • Humana
  • Nevada Medicaid
  • Medicare
  • Molina Healthcare
  • Prominence Health Plan
  • SilverSummit Health Plan
  • Tricare
  • UnitedHealthcare / Optum

Medicaid plans in network: Anthem Medicaid, Molina Medicaid, Nevada Medicaid, Silversummit Health Plan Medicaid and United Healthcare Health Plan of Nevada Medicaid. Optum Medicaid isn't in network, and Medicaid can't be billed out of network.

Your plan decides separately whether it pays for Spravato itself. Plans may require prior authorization and records of the antidepressants you've tried, so we check your benefits before treatment starts. You can also check your plan.

No insurance? Self-pay consult visits are $150. That covers the visit, not the medication or treatment sessions, so ask for the full cost before you start.

Spravato questions

Can I get Spravato online?
No. Spravato is only given in person at treatment centers certified in the FDA's Spravato REMS program. A telehealth visit can't replace the in-clinic session, and Spravato can't be shipped to your home.
Can I take Spravato at home?
No. Every dose is taken at a certified treatment center while a healthcare provider watches, followed by at least 2 hours of monitoring. Patients don't take the nasal spray home.
Is there an online Spravato prescription?
No. Spravato isn't filled at a retail pharmacy for you to pick up. Certified pharmacies send it only to certified healthcare settings, and that's where you use it.
Where does Anywhere Clinic give Spravato?
Only in person, at Calm Clinic, our Las Vegas office at 4029 Dean Martin Dr, Las Vegas, NV 89103. Spravato consults are with Dr. Grant Bullock, DO. Book a consult online from this page or call (702) 848-2256.
What is Spravato?
Spravato is esketamine nasal spray. It's FDA-approved for treatment-resistant depression in adults, used alone or with an oral antidepressant, and for depressive symptoms in adults with major depressive disorder who have acute suicidal thoughts or actions, used with an oral antidepressant. It contains esketamine, a Schedule III controlled substance.
How is Spravato different from ketamine?
Esketamine, the medicine in Spravato, is one of the two mirror-image forms of ketamine. Spravato is FDA-approved for the depression uses above and is only given in certified treatment centers. Generic ketamine is FDA-approved as an anesthetic. When clinicians prescribe ketamine for mental health it's off-label, and it is not FDA-approved for any psychiatric condition. Both are Schedule III controlled substances.
What is the treatment schedule?
For treatment-resistant depression, the label's schedule is two sessions a week in weeks 1 to 4, one a week in weeks 5 to 8, then weekly or every 2 weeks from week 9, at the least frequent schedule that keeps you well. Your clinician checks whether it's helping at the end of week 4. For depressive symptoms with acute suicidal thoughts or actions, the course is two sessions a week for 4 weeks.
What is treatment-resistant depression?
In the Spravato clinical trials, it meant adults with major depressive disorder who, in the current episode, hadn't responded adequately to at least two different antidepressants taken at an adequate dose for an adequate time.
What happens during the observation period?
After the dose you rest at the clinic for at least 2 hours while a healthcare provider monitors your breathing and checks your blood pressure, then confirms you're stable before you leave. Don't drive or operate machinery until the next day after a restful sleep, so arrange a ride home.
What side effects could I experience?
The most common are dissociation, dizziness, nausea, sleepiness, a spinning sensation, numbness, anxiety, low energy, higher blood pressure, vomiting, feeling drunk and headache. They usually happen right after a dose and go away the same day. Don't eat for 2 hours or drink for 30 minutes before a session.
Can I use Spravato if I'm pregnant or breastfeeding?
Spravato isn't recommended during pregnancy because it may harm an unborn baby, and breastfeeding isn't recommended during treatment. If you could become pregnant, talk with your clinician about pregnancy planning and prevention before you start, and tell them right away if you become pregnant during treatment.
How quickly might I see improvements?
In the main short-term study of adults under 65, people using Spravato with a new oral antidepressant improved more by week 4 than people using a placebo spray with a new oral antidepressant. Not everyone responds.
Does insurance cover Spravato?
Spravato consults at Calm Clinic are in network with these Nevada plans: Aetna, Anthem / Carelon, Cigna / Evernorth, Humana, Nevada Medicaid, Medicare, Molina Healthcare, Prominence Health Plan, SilverSummit Health Plan, Tricare and UnitedHealthcare / Optum. Optum Medicaid isn't in network, and Medicaid can't be billed out of network. Your plan decides separately whether it pays for Spravato itself and may require prior authorization, so we check your benefits before treatment starts. Self-pay consult visits are $150; that covers the visit, not the medication.

Spravato at a glance

How Spravato works at Calm Clinic

In person only

Every dose is taken at a REMS-certified center while a healthcare provider watches, with at least 2 hours of monitoring afterward. Ours is Calm Clinic in Las Vegas.

FDA-approved

Treatment-resistant depression in adults, alone or with an oral antidepressant, and depressive symptoms with acute suicidal thoughts or actions, with an oral antidepressant.

A set schedule

Two sessions a week for the first 4 weeks, weekly in weeks 5 to 8, then weekly or every 2 weeks. Your clinician checks progress at week 4.

Benefits checked first

Consults are in network with 11 Nevada plans. We check what your plan pays for Spravato itself before you start.

Pink brain illustration representing mental health and brain wellness.

What a Spravato session at Calm Clinic looks like

Plan on staying at the clinic for at least 2 hours after each dose.

Check-in and blood pressure

Your blood pressure is checked before the dose, and your clinician confirms Spravato still fits your treatment plan.

Supervised nasal spray

You use the nasal spray yourself at the clinic while a healthcare provider watches.

At least 2 hours of monitoring

You rest while your breathing and blood pressure are monitored, and leave once you're stable. No driving until the next day after a restful sleep.

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